Whooping-Cough *
نویسندگان
چکیده
Following the isolation of the pertussis bacillus by Bordet and Gengou' in 1906, anticipation of methods of control of whoopingcough was inevitable. This discovery gave impetus to experimental and clinical investigations on various aspects of the whooping-cough problem. The isolation of the apparent causative agent, the introduction of new bacteriologic aids in early diagnosis, the transmission of the disease to monkeys, attempts at specific prophylaxis and therapy, and, finally, the more recent knowledge on the mutation of Hemophilus pertussis,-all this extensive research extending over a period of twenty-six years has contributed valuable information concerning the disease. Nevertheless, whooping-cough cannot be adequately and practically controlled; it still flourishes and continues to surpass measles as a cause of infant mortality. The outstanding contribution directed toward the control of whooping-cough was the introduction of the cough-plate method in 1916 by Chievitz and Meyer2 as a simple and convenient aid in the early diagnosis of the .disease. It is logical to assume that the earliest diagnosis possible during the period of greatest contagion will aid appreciably in preventing the spread of an infectious disease, yet it is surprising to note the hesitancy of the medical profession and epidemiologists in general to utilize this valuable aid in the diagnosis of whooping-cough, in spite of the fact that the method has proved effective in the hands of various investigators in this country and abroad. The early diagnosis of scarlet feVer and diphtheria is given much consideration, but the early diagnosis of pertussis, a disease which causes more deaths than these two combined, is too often disregarded. Early diagnosis favors early quarantine, and if the latter is properly executed the incidence of the disease will drop proportionately. The main objection raised against the general use of the coughplate is that it involves considerable technical difficulties, namely,
منابع مشابه
Preparation and Evaluation of Stained Pertussis Antigen for Serodiagnosis of Whooping Cough
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عنوان ژورنال:
- The Yale Journal of Biology and Medicine
دوره 5 شماره
صفحات -
تاریخ انتشار 2008